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TargetView™ – Frequently asked questions

 

What file types can be processed?

TargetView processes chromatographic datasets with *.d, *.cdf, *.raw and *.lsc file extensions.

Are any other programs necessary before using TargetView?

No, although you can only make full use of TargetView’s functionality if you’ve also installed the NIST Search program. This is also available separately from ALMSCO.

Is the original data overwritten during TargetView processing?

No. The original files are imported into TargetView but copies are always retained.

Do I need to have my own spectral library before using TargetView?

No. You can use the NIST library to create your own – either by direct selection, or following processing of a chromatogram. Alternatively, if you’re confident of the identity of a component (if for example, you’ve run a standard sample), then you can generate a library from the mass spectrum produced by TargetView.

How big can my spectral libraries be?

Libraries can be any size, although larger libraries will take longer to process. You can also search your spectrum against a large commercial library such as NIST, which contains hundreds of thousands of compounds.

Does the background compensation process compromise the results?

No – this is one of the key innovations of TargetView. In all but the most extreme cases of column bleed or solvent contamination, TargetView seamlessly identifies the exact ions associated with the contaminants, and intelligently extracts them from the data, leaving behind just those ions associated with chromatographic peaks. This gives far more reliable results than other packages that just ‘cut off’ the baseline.

How long does it take to process a chromatogram against a target library?

This depends on the speed of your computer, the size of the file and number of compounds in your target library. As a rough guide, a moderately complex chromatogram, run against a 20-component library on a standard computer, should be completed within minutes.

Can TargetView handle more than one file at once?

Yes. The batch-processing option allows multiple files to be run against a single target library. As well as the individual target reports, a log file is produced confirming that the files have been processed.

Can TargetView handle compounds with similar mass spectra?

Yes. You can add expected retention times to library compound, and (so long as the compounds can be separated chromatographically), these can be used to aid identification.

Can TargetView distinguish between co-eluting compounds?

Yes it can, even when the peaks are at identical retention times – so long as the peak shapes are different (which applies in the vast majority of cases). However, if the compounds have co-eluting peaks and similar mass spectra, then it is wise not to rely solely on the matching factor for identification, and this is where TargetView’s ability to compare retention times can be useful.

Is it possible to assess the quality of the target match?

Yes. TargetView produces a matching coefficient for each target match identified. This is a score on a scale from 0 to 1 that tells you how similar the spectrum obtained is to the one in the target library.

Can TargetView reports be exported?

TargetView reports can be printed, opened in Excel®, or copied-and-pasted in tab-separated text format.

Has TargetView been tested on Windows XP? Yes, TargetView has been tested with Windows XP Service Pack 3.

Can I try before I buy?

Yes, you can click here to try TargetView for FREE.

I'm convinced, can I purchase online?

Yes, TargetView can be purchased from the Markes International online shop here.

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